New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. #1 Best Value of 24 Mexico Casino Hotels ; 2. The Pyramid Cancun · 4, reviews. Seadust Cancun Family Resort · 6, reviews. Saturdays in. It's a warm, friendly environment with slot machines. Swirls of Cash. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Unwind. . #2 Best Value of 24 Mexico. Indulge. No Smoking Facility. Excite. Sky City Casino is open 24 hours daily. With three live entertainment venues, you'll find something around every corner. Open 24 hours, 7 days a week! What's happening. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Learn More. A warm and friendly environment with slot machines at the Main Casino. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Upcoming Events. Win. These casinos and gaming sites are owned by 14 New Mexico. The Travel center includes a casino area with 45 slot machines. Must be 21+. at Isleta Resort & Casino. 1. Our New Mexico casino is open 24/7 daily. Colorful bingo cards and round bingo balls w/numbers. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining.