Our New Mexico casino is open 24/7 daily. . New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. With three live entertainment venues, you'll find something around every corner. Open 24 hours, 7 days a week! What's happening. #2 Best Value of 24 Mexico. The Pyramid Cancun · 4, reviews. It's a warm, friendly environment with slot machines. Learn More. No Smoking Facility. #1 Best Value of 24 Mexico Casino Hotels ; 2. Seadust Cancun Family Resort · 6, reviews. Must be 21+. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. These casinos and gaming sites are owned by 14 New Mexico. A warm and friendly environment with slot machines at the Main Casino. Upcoming Events. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. Indulge. at Isleta Resort & Casino. Swirls of Cash. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Sky City Casino is open 24 hours daily. The Travel center includes a casino area with 45 slot machines. Excite. Win. Saturdays in. Colorful bingo cards and round bingo balls w/numbers. 1. Unwind.